Process vs Product Drama in Education Essay Example | Topics and Well Written Essays - 2000 words - 1

Process vs Product Drama in Education - Essay Example According to the paper the intrinsic, imaginative of the student was part of learning and was based on the intrinsic needs of the individual. A new student-centered approach became a primary and secondary method of approaching process vs. product drama in education in England†¦ the exploration of intrinsic, imaginative needs from the ‘mind’s eye’ or inner visualization of the student was the basis of discussion and practice for production and performance moving into the 20th century. Thus, many of the ‘product vs. process drama’ perspectives were based on the intrinsic processes of the student-centered learning experiences. Teacher and drama education practitioner, Harriet-Finlay Johnson   claimed freedom of expression concerning ‘aesthetic valuation’ of product, production and performance of plays†¦a student’s aesthetics and perspective should be the diverse ‘lens’ through which the value of dramatic proce ss or theatrical experiences be judged. Analysis of the research literature is a predominant method by which this thesis.

Techniques in Understanding Planets and Stars2 Essay

Techniques in Understanding Planets and Stars2 - Essay Example Other natural light sources like the fire also produce electromagnetic radiations. The light bulbs and the fluorescent bulbs produce all the seven colours of the rainbow when the light shines upon the spectrometer. The reason being that the white light produced is split up by the spectrometer. A sodium street lamp generally produces only one light type when struck upon the spectrometer. The sodium component in the bulb only produces a yellow light. The spectrum shows a dazzling yellow band. Extra bands of colours are produced under high pressure. Street lamps are typically high-pressure sodium lamps that give a white light. When viewing a white block above an LCD using the spectroscope, three bands of colours are produced- red, green, and yellow. TVs and computer monitors use a combination of these three colours to produce millions of colours. The feature of the light source that get represented in the spectrum is illumination. It measures the light output from the different sources of light. Illumination is the light distribution on a surface that is horizontal. Thus, in this experiment the spectrum distribute light in the spectrometer that gets assembled. Therefore, what gets analyzed in this experiment is the distribution of light from different spectrums in horizontal surfaces. There is also the examination of the number of components that a light source can be broken up into using a spectroscope/prism (Fisher & Erickson, 2010). Spectrometers in an instrument that splits colour into a higher band numbers. The ordinary color splits up the light into three colors including green, blue and red. Spectrometers are very significant studying celestial objects. Spectrometry allows people to study and measure the celestial bodies’ velocities and distances on the cosmological scales. When the object is moving, the light wavelengths it emits is shifted either towards

How has information technology changed the daily lives of enlisted men Research Paper

How has information technology changed the daily lives of enlisted men and women serving in conflict zones overseas - Research Paper Example With the aid of academic literatures, this paper also aims to define information technology as used in this paper to provide a background as to how information technology relates to the US military, and provide a historical background of the utilization of IT in the US military forces to probe on how technology has affected military forces across different eras. 2.0 Information Technology (IT) Generally, Information Technology or IT is the processing of information by the computer systems which are greatly used for communication, data security and storage (Stoyles, Pentland, & Demant, 2003, p. 4). Thus, information technology helps the people in gathering, sharing and storing of data in a convenient and fast manner. Moreover, according to Yadav (2006, p. 2), information technology includes television sets, published works, computers and the Internet (which are common technologies used at home and offices) and any other media platforms where people can acquire information. In the cont ext of the military forces, information technology relates to the Revolution in Military Affairs (RMA) wherein information technology is used for weaponry, surveillance mechanisms, processing of information, and organizational transformations of different military units (Goldman, 2005, p. 1). These benefits center on the organizational advantage of the force. Part of the utilization of information technology of the US corps is also to provide personal benefits to the military soldiers as privatization of housing through IT, skills development and telemedicine programs. 3.0 IT and the Military: History In the early days of war fighting, various nations have adopted new technologies that brought radical changes in fighting. The end of World War II has marked the birth of atomic bombs where it was later developed to hydrogen bombs (Perry, 2004, p. 235). As people become more knowledgeable on the use of technology, the weapons and war instruments have also metamorphosed to a more advanc ed state. Furthermore, as the Soviet Union and the United States of America are creating war technologies based on fatal situations, both countries have developed missiles (Perry, 2004, p. 235). War weaponry continuously evolved which now includes new systems as satellites, smart sensors and new aircrafts to name a few. However, during the 1990s, as information technology slowly shapes the American society, and likewise, the US military has also acknowledged the importance of such technological advancement to further develop its strategies and principles that will ensure the dominance of the forces of the US military (Dombrowski & Gholz, 2006, p. 1). As information technology in the military forces centers on the war fighting improvement, they have implemented â€Å"network-centric warfare,† thereby providing a centralized infrastructure that allows communication, detection mechanics, commanding and controlling systems, combat information and battleground bearings among other s that can be accessed by various military personnel (X. Wang, Wei, & H. Wang, 2012, p. 573). From the mechanical war instruments, the advent of more advance technologies paved way for the

Take Home Final for Information Assurance and Management Class Research Paper

Take Home Final for Information Assurance and Management Class - Research Paper Example This process ensures evaluation of venerable threat to the company, a system is developed where the threats are usually eliminated (Steven 3). A large company needs a system that provides assurances from the top down because the top management hold most of the crucial information and this makes them more venerable compared to other workers. A system should be created that seek, to protect and minims available threat among top management this is because of, crucial information that the person holding these offices have. For example it would be of relevance’s to have a top-down system in World Bank, where IA practitioner usually makes sure that, the higher the offices the more threats are posed and should be evaluated most, compared to a junior employee who is a clerical officer and would not be having any crucial information that poses as any threat. The CEO of such a company should be placed in a system that gives assurance protection of all his working with a third party, thi s is because he/she is the central nerve of the company (Cook 6). If a company was small in size, I would go for same level type of assurances, because it would be possible to have assurances in the same at all levels considering the size; this would be facilitated by the fact that; supervising small companies is easier compared to big companies. Take the example of the World bank, it has a lot of departments and its work forces is huge making it impossible to have the same assurances at all levels. A baseline set of IT assets They are two types of data IT that need to be incorporated into the shop this is; authorized asset data and deployed asset data. Authorized asset data should be set up in the shop, to record all activities of purchasing, selling and storing goods. The shop does not have any system that records activities that take place in the shop. This makes the owner venerable from loss of information; the only storage of activities that have taken place, is the ownerâ€⠄¢s brain and is likely to forget. This process authorized asset data, gathers all information and records it in a backed up storage for future references, it’s also used to make sure all transactions are accounted for and they can be tracked down easily (Roger 2). Deployed asset data are a process of collecting information, this process is actually in use in the shop but it’s not properly used, this is because the camera system placed in the shop doesn’t have a recording backup capability, it's only used for surveillances. Being a shop that is very vulnerable to be attacked, strategic positioning and recording cameras should be placed inside and outside the shop to enable monitoring of movement around the shop 24/7 to ensure maximum security. The owner cannot be the security officer at the same type sell jewels; he should employ a security person. The risks that are coming out in this shop are; breakage at night and organized gangs posing as customers during da y time. On the threat of breakage at night, the owner should employ a security officer who should take care of the shop, because the jewels are leaving them at night are likely to be an easy target when they is no one to look over them. Placing a security guard at the entrances, should be of ability to make sure all of the people who are entering the shop don’t carry any weapon of try to steal by pretending they are buying (Fowler 3). Tailored information assurance framework Question 2 Classification

How ratio analysis provides a meaningful comparison of a company to Essay

How ratio analysis provides a meaningful comparison of a company to its industry, chief competitors, or to any other well run firm - Essay Example These techniques help to compare a company’s performance with its chief competitors in same industry as well as monitor the company’s progress over time. Accounting ratios is an important tool for financial statement analysis. A ratio is defined as relation between two numbers expressed as fraction or as percentage. When such relationships are derived from the financial statements, they are called accounting ratios (Kim & Ayoun, 2005, p.2). Accounting ratios have immense application in interpretation of financial statements by helping perform both intra-firm and inter-firm comparison. Intra-firm comparison helps to measure the performance of the company on Y-O-Y basis while inter-firm comparison helps to evaluate Company’s performance with its competitors. Ratios can be broadly classified into income statement ratios (derived from income statement), balance sheet ratios (derived from balance sheet) and composite ratios (one item from balance sheet and another from income statement). They help to evaluate the firm’s ability to honor its short term or current obligations. It is an indicator for the measure of working capital management. The firms’ short term obligations include carrying out day to day operations, payments to creditors for purchase of raw materials, payment of daily wages of laborers, outstanding expenses and bills payables, etc. These current liabilities are financed by current assets (Bragg, 2012, p.73). It is the ratio of total long-term debt to total asset. While a low ratio provides security to creditors a high ratio helps the management to trade on equity. Hence it is also called the leverage ratio (Drake, 2008, p.9). It is the ratio of long term debt to shareholders’ fund (Equity shares, retained earnings, preference shares, and fictitious assets). Form the investors’ point of view a

The human nature Essay Example for Free

The human nature Essay How much is human frustration worth? Is it worth losing a chance to buy a present for the girl you like? Or is it worth participating in a lottery which is nothing more but a silly tragic fatal ritual? I was asking these questions while reading James Joyces Araby and Shirley Jacksons The Lottery. For me, both stories represent the ultimate point of human despair: at this point, the person is no longer able to control his (her) life and surrenders under the pressure of overwhelming circumstances. I think that frustration is the central element of both stories; it touches the depth of the readers soul and turns into disruptive revelation about the perversity and hideousness of the human nature. Human strength and endurance has no limits; human evil and self-interest are unlimited, too. James Joyces Araby shows human frustration in its powerlessness in the face of insuperable circumstances. Every morning I lay on the floor in the front parlour watching her door. [†¦] When she came out on the doorstep my heart leaped (Joyce 62). The whole life of the anonymous narrator is filled with joy of seeing the young lady walking in front of him, and passing her before their ways diverge. He lives his life from morning to morning, when he will see Magans sister again. This is the life full of waiting; this is the life full of expectation, anxiety, dreaming and almost physical attraction. The same is the life of villagers whom Jackson describes in her The Lottery. It is the life full of expectation mixed with the feeling of threat, fear, and imminence of the coming end: Bobby Martin already stuffed his pockets full of stones, and the other boys soon followed his example, selecting the smoothest and roundest stones (Jackson 10). As the young boy cannot wait to visit the bazaar I could not call my wandering thoughts together. I had hardly any patience with the serious work of life which, now that it stood between me and my desire, seemed to me childs play (Joyce 63), the villagers cannot wait to hear when the new victim of the annual ritual will be declared: guess we better get started, get this over with, sos we can go back to work (Jackson 13). The deeper Joyce goes into the young boys soul, the larger is the prairie between his promise to visit the Araby bazaar and the realization of his inability to fulfill the promise: Nearly all stalls were closed and the greater part of the hall was in darkness (Joyce 65). How bright and shockingly sincere Joyces revelation could be, Jacksons story has gone far beyond Joyces reasonable limits. Jackson has gone even deeper to the moment of unexpectedness which emphasized the unlimited nature of human mercenary character. In the light of Jacksons The Lottery, Araby produces an impression of the boy’s relatively mild reconciliation with the surrounding opportunities and circumstances. Moreover, I feel that Joyce still leaves some hope that everything will change: ultimately, there will be another bazaar and another girl, although the young boy does not yet understand it. On the contrary, Jackson uses unexpectedness to emphasize how far human coldness, rationality, and perversity can go; the author shows, how easily humans turn into beasts when they pursue material interests, leaving no hope to escape the lottery’s trap. Jackson shows how human desire to kill turns into a usual feeling, when it becomes regular for and acceptable by other community members: the whole lottery took less than two hours, so it could begin at ten oclock in the morning and still be through in time to allow the villagers to get home for noon dinner (Jackson 10). Conclusion Both stories end up in frustration; for Joyces character, frustration is reflected in the hollow sound of two pennies that fall against the sixpence in my pocket (Joyce 66). A creature driven and derided by vanity (Joyce 66) is the end result of Joyces striving towards recognition and love. For Tessie Hutchinson, frustration becomes real as she holds the slip of paper that has a black spot on it, the black spot Mr. Summers had made the night before with the heavy pencil in the coal company office (Jackson 17). Later, this frustration turns into the feeling of inevitability of tragedy, when a stone hit her on the side of the head (Jackson 17). In both stories, frustration is the shocking reflection of the human hideousness, cruelty, and indifference which leave no chance for spiritual and physical resurrection. Works Cited Jackson, S. â€Å"The Lottery†. 10-17. Joyce, J. â€Å"Araby.† 61-6.

Evaluation of Sustained Release Matrix Tablets of Cilostazol

Evaluation of Sustained Release Matrix Tablets of Cilostazol Development and in Vitro-in Vivo Evaluation of Sustained Release Matrix Tablets of Cilostazol Keywords:Cilostazol; Pharmacokinetics; ER Matrix Tablet; In Vitro Kinetics; ABSTRACT The objective of this research had to manufacture extended release matrix tablet of Cilostazol and to evaluate its in vitro drug release and in vivo absorption. The dosage form was designed by selection of various polymers such as Hypromellose, Kollidon SR, Xanthan gum, Ethyl cellulose, Eudragit Polymers. Microcrystalline cellulose and lactose as dilutents to build matrix tablets and povidone as granulating binders. The tablets were prepared by Direct compression, wet granulation and Melt extrusion techniques. Optimized formulation of Cilostazol matrix tablets was prepared by using 7% HPMC K100M polymer, 39 % MCC, 3% of povidone as binder. Matrix tablets were compressed with optimized free flowing granules of uniform drug content. This in vitro drug release showed the extended the release period up to as per desired specifications. The matrix formed by HPMC, MCC and Povidone had been showed satisfactorily with the controlled resistance. Bioavilability study of this wet granulation do sage formulation in rabbit model showed 24 h sustained drug release in vivo. A correlation (R2= 0.9833) was founded between the in vitro drug release and the in vivo drug absorption. The results suggested that wet granulation with is a satisfactory method to develop a sustained release Cilostazol and it can be Performed therapeutically better than conventional IR dosage form. 1. Introduction In this study the Cilostazol sustained release matrix tablet was developed with various polymers. Since the IR dosage form produces and side effect head of ache due to drug oscillation in plasma. The challenge become to develop a matrix tablets are due to drug morphology and highly insoluble in nature . In the present study, a sustained release dosage form of Cilostazol has been developed that enables less frequent administering of drug . Matrix tablets of Cilostazol were formed by appropriate combination of HPMC and Povidone and lactose monohydrate,MCC and Kollidon K30 was chosen for matrix tablet to extend duration of drug release. Cilostazol and its metabolites are inhibit the platelet aggregation and exert vasodilatory action by inhibiting phosphodiesterase activity and cAMP degradation with a resultant increase in cAMP in platelets and blood vessels The objectives of research were: 1) To analyze the physical and chemical characters of prepared Tablets 2) To elucidate the effect of polymers and to study the release kinetics, 3) in-vivo study for the stable formula. 2. Materials and Methods 2.1. Materials Cilostazol was obtained from IPCA lab, Mumbai, India. Hypermellose (Methocel K100M CR), Povidone K30 received as a gift sample from Colorcon Pvt Ltd. Kollidon K30 was obtained from BASF. All other Reagents were purchased from local suppliers, India and were of analytical grade. 2.2. Drug and Excipient Interactions Drug Excipient interaction study was investigated by DSC (differential scanning calorimeter). The DSC Thermo gram of only drug and Drug+Excipient mixtures were noted. The samples were separately packed in aluminum cells and kept a set in Metler TA 4000 Thermal analyzer. 2.3. Formulation 1. Dispensing: All the ingredients were dispensed accurately as per formula quantity. 2. Sifting: Measured quantity (refer table no.4.5) of Cilostazol, Microcrystalinecellulose (Avicel PH-101), HPMC K100M, were passed through 30#, Microcrystalinecellulose(PH-102), Aerosil-200, through 40#, yellow oxide of iron and Magnesium stearate were passed through 60# . 3. Mixing: Measured quantity (refer table no.4.5) of Cilostazol, Microcrystalinecellulose (Avicel PH-101), were mixed in polybag for 15 min, to it added yellow oxide of iron and mixed for 5 min. in RMG at 2.4 RPM . 4. Preparation of Binder solution: Measured quantity (refer table no.4.5) of IPA and Water were poured in stainless steel beaker, to it added PVPK-30 with stirring continuously by glass rod till dissolved completely and clear solution is obtained. 5. Wet Granulation: Granules were prepared by wet granulation method in RMG at 2.4 RPM for 15 min, using step 4 binder solution. Prepared granules dried at 60  ºc till LOD reaches less than 2.5% and finally sifted through 30#. 6. Mixing: Mixed the measured quantity (refer table no.4.5) of Microcrystaline cellulose (Avicel PH-102), HPMC K100M, Aerosil-200, in polybag for 15 min with granules obtained in step 5. 7. Lubrication: Above granules are lubricated with measured quantity of magnesium stearate In the trial 5 concentration of HPMC K100M is reduced from 10% to 8% and trials 6,7,8 from 10% to 7% . 2.4. Physical Characterization of Tablets The prepared tablets were subjected to various physical characterization studies. Weight variation test was performed with 20 tablets with an electronic balance. Tablets hardness was determined using Monsanto (Standard type) tablet hardness tester. Thickness was measured by a venier caliper (Mitutoyo, Japan). Friability was calculated using a Roche friabilator (Basel, Switzerland) 2.5. Drug Content of Tablets (Assay by HPLC) Cilostazol USP: Chromatographic Conditions: The drug content of the formulated tablets was estimated by HPLC method. Column: Stainless steel column packed with octadecylsilane silica gel for chromatography ,c18 ,150Ãâ€"4.6 mm,5 µm(Inertsil ODS-3 is suitable) Mobile phase::Acetonitrile:Mthanol:Water(7:3:10by volume), filter and degas. Flow rate: 1.0ml / min Wavelength: 254nm Diluent: Methanol Injection Volume: 10 µl Temperature: 270C ± 10C Retention time: Cilostazol- about 9.4 minutes. Cilostazol was analyzed by HPLC at a wavelength of 254 nm. 2.6. In Vitro Dissolution Studies In-Vitro dissolution Studies (Dissolution analysis by HPLC) Dissolution testing for the amount of drug-substances released was studied using the following dissolution parameters: Table : Dissolution parameters and specifications for Cilostazol Acceptance criteria : As given table no.4.15 Dissolution Parameters:Medium: 900 ml, 0.3% SLS in 6.8 Phophate bufferApparatus: USP Apparatus 2Paddle Speed: 75 RPM Temperature:370C  ± 0.50c. Duration:1,4,8,12,24 hours Chromatographic Conditions: Instrument: HPLC(Hitachi) Column: Stainless steel column packed with octadecylsilane silica gel for chromatography, C-18, 150cmÃâ€" 4.6mm, 5 µm (Inertsil ODS-3 is suitable) Mobile Phase: Acetonitrile:Mthanol:Water(7:3:10 by volume) filter and degas. Flow rate: 1.0 ml/min Wavelength: 254nm Injection Volume: 20 µl Diluent: Methanol, Dissolution Medium Temperature: 270C  ± 10C. The release studies were conducted in duplicate. Mean % cumulative drug release was plotted against time (hours). 2.7. Drug release Kinetics and Mechanism Kinetics of drug release was determined by fitting data to Table 1. Composition of extended release matrix tablet of Cilostazol different models such as zero order (M = kt), first order equation (M = lnM0+ kt), Higuchi model (M = k√t) and KorsemeyerPeppas equation (M = ktn). The value of n = 0.5 denotes case I diffusion (Fickian), 0.5 n = 1, for case II transport and n > 1 for super case II transport. Where M is the amount of drug (%) released after time t; Where M0is the amount of drug released at (0) zero time; k is the release rate constant, n is the exponent. Drug release following particular mechanism is judged by the linearity of plot 2.8. Stability Studies Stability studies were conducted on SR Tablets of select batch to assess their stability with respect to their physical appearance, drug content and release characteristics after storing at 25ËÅ ¡C under 60% relative humidity (RH) and 40ËÅ ¡C under 75% RH for 6 months [8]. 2.9. Pharmacokinetic Evaluation The animal studies were performed as per guidelines for the Care and Use of Animals that were approved by the Animal Ethics Committee. Male rabbits (Albino) with average weight of 2.5 kg were housed in standard cage individual, which well ventilated with air, humidity and temperature control. 50 mg equivalent weight of Cilostazol sustained Release Tablets with and 50mg equivalent weight of Cilostazol 50mg IR tablet was administered to 2 groups orally (N = 4) via silicone rubber gastric intubation tube. A wooden rod was kept between the jaws of rabbit’s mouth. A gastric tube was centrally placed over the hole in mouth (21.22). With the help of gastric intubation tube the tablets were administered in to the stomach of rabbit by set on the tip in it. After administered the oral dose, 5 ml of water was given to facilitate the admittance of the tablets. Rabbits were kept fasting over night but access to water ad libitum; In a heparin zed branule (G22, G24) 2 ml of blood samples were collected, which placed in the marginal ear vein , at each of the pre determined times i.e., 0.25 Hr, 0.5 Hr, 1 Hr, 2 Hr, 4 Hr, 6 Hr, 8 Hr and 24 Hr after administration:Samples were transferred to eppendrof centrifuge tube and centrifuged at 3000 rpm for 10 min. The separated organic layer will be collected and evaporate to dryness under a gentle steam of nitrogen gas. The obtained residues will be reconstituted in organic solvent with vortex mixing, from which aliquot will be injected to HPLC system . supernatant plasma was separated and transferred and stored at –20ËÅ ¡C until Analyzed. in to 96 well plate 2.10. In Vivo Data Analysis The maximum plasma concentration (Cmax) and the time to reach the maximum concentration (tmax) were directly obtained from the observed values. The area under the curve up to 24 h after administration (AUC) was calculated by the trapezoidal rule from the observed values. 3. Results and Discussion In this study, the matrix tablets were prepred using various types of polymers and different composition. of polymers (Table 1) of matrix forming polymers (HPMC, sodium CMC and MCC) with the help of granulating agent, PVP was used as Binder. In vitro studies conducted for all the formulations. Extended release of drug was in the order of CW1 Figure 1). Rate of drug release was significant (p Figure 1, CW5). It seems the mechanism is by diffusion method. Physical characteristics of matrix tablets were shown in Table 2. There was no any significant burst effect in the optimized HPMC matrix tablets that showed a low possibility of dose dumping and avoids toxicity (in vivo). The Release kinetics of matrix tablets was determined by fitting the drug release data in different established models they are zero order, first order, Higuchi model, Korsemeyer-Peppas equation.Table 3shows values of regression coefficient, release constant and exponent n. First order release data was not satisfactory. The data suggested that kinetics of drug release of DVF5 was best explained by Korsemeyer-Peppas equation (R2= 0.991, n = 0.60). This indicated combined effect of diffusion and erosion mechanism on the release of drug. The stability results of storing at 25ËÅ ¡C/60% RH and 40ËÅ ¡C/75% RH for 6 months as per ICH guidelines evidenced any change in physical parameters and appearance and very slight change in dissolution pattern. Based on the available stability data 2 years shelf life can be provided. Figure 1. In vitro release profile of Cilostazol SR tablets. Table 2. Drug release kinetic of Cilostazol SR tablet formulations. Next, the stable formula were designated for its in vivo test in rabbit. Plasma concentration and pharmacokinetic parameters after oral administration of formulated ER matrix tablet CW5 and Cilostazol IR tablets 50mg were summarized inFigure 2andTable 3. No sustained blood level was observed after oral administration of the IR formulation. The formulated matrix Tablet (CW5) showed significant lowerCmaxthan the IR formulation (P max(tmaxis 6 hr) as compared with immediate release formulation (tmaxis 0.55 hr). The AUC increased from 11190.30 hr*ng/ml to 295396.49 hr*ng/ml for ER tablets. Values of Cmaxand tmaxclearly indicated that the drug release was sustained to about 24 hours after oral administration in rabbits (n = 4). CW5 Tablets maintained prolonged plasma concentration up to about 24 hours. The sustained plasma concentration of new formulation (CW5) indicates its extended drug release in vivo absorption. The Results demonstrated that the hydrophilic polymers were successfully utilized for formulating Cilostazol extended release matrix tablets. By wet granulated with povidone . Moreover the extended release matrix tablets have a unique advantage of lessening chance of dose dumping and to avoid side effects. The investigated extended release matrix tablets were adequate to maintaining constant plasma level of Cilostazol up to 24 hours in rabbits. Figure 2. Profile shows mean plasma concentration of Cilostazol against time, following oral administration of IR tablets and SR Tablets (CW5) to rabbits. Data are represented as mean  ± SD (n = 4). Table 3. Mean ( ±SD) pharmacokinetic parameters of Cilostazol in Rabbits (n = 4) orally administered with IR tablets and ER tablets CW5 (50 mg). 4. Conclusion A new sustained release formulation of Cilostazol has been developed for its in-vitro drug release and in-vivo absorption. Extended release matrix tablet were found to be an effective to maintain the drug level in plasma. Bioavailability studies can be carried out to assess the usefulness of this formulationand in comparison with existing IR products in the market formulations on healthy human volunteers.